Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679

Abstract Since the classic studies of Alexander Flemming, Penicillium strains have been known as a rich source antimicrobial substances. Recent identified novel metabolites produced by sclerotiorum that antibacterial, antifouling and pharmaceutical activities. Here, we report isolation P. (LM 5679) from Amazonian soil carry out culture-based study to determine whether it can produce any secondary metabolite(s) are not thus-far reported for this genus. Using submerged culture system, were recovered solvent extract followed thin-layer chromatography, nuclear magnetic resonance, mass spectroscopy. One metabolite was isolated 5679); phenolic compound 5-pentadecyl resorcinol widely an antifungal, is diverse plant species. This previously in species only found once before fungi (that time, Fusarium). discuss activities context its mode-of-action hydrophobic (chaotropicity-mediated) stressor.